Pharmacology: Drugs for chronic gout
Phenylbutazone: effective. anticoagulatnes and interacts with oral antidiabetics, increasing its effects
Indomethacin (indole derivatives, which are non-steroidal anti-inflammatory): routes: oral, intramuscular, rectal
Adverse reactions: headache, dizziness, vertigo
chronic gouty disease treatment: uricosuria and inhibitors of uric acid formation
Probenecid: benzoic acid derivative via
:
oral mechanism of action: it inhibits the reabsorption of uric acid
action: increases the urinary excretion of uric acid
indications: gouty patient young
sulfinpyrazone Sulfinpyrazone is a derivative of phenylbutazone (anti-inflammatory and uricosuric)
route of administration: oral, bound to proteins
metabolism: hepatic excretion
:
renal mechanism of action: prevents uric acid
reabsorciond and action: increases urinary excretion of uric acid
indications: chronic gout
adverse reactions: gastrointestinal irritation, hypersensitivity
iterations: anticoagulant drugs, oral antidiabetic
benzbromarone
route of administration: oral
mechanism of action: it inhibits the reabsorption of uric acid
action : increased urinary excretion of uric acid
indications:
gouty patient interactions: interact with aspirin or sulfinpyrazone
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